Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gcg  glucagon   (Synonyms: GLP-1, Glu, glucagon-like peptide I, PPG)
Results	Reference
1	J:98803 Collombat P, Hecksher-Sorensen J, Broccoli V, Krull J, Ponte I, Mundiger T, Smith J, Gruss P, Serup P, Mansouri A, The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the {alpha}- and {beta}-cell lineages in the mouse endocrine pancreas. Development. 2005 Jul;132(13):2969-80
1*	J:113424 Dichmann DS, Yassin H, Serup P, Analysis of pancreatic endocrine development in GDF11-deficient mice. Dev Dyn. 2006 Nov;235(11):3016-25
1	J:129665 Fujikura J, Hosoda K, Iwakura H, Tomita T, Noguchi M, Masuzaki H, Tanigaki K, Yabe D, Honjo T, Nakao K, Notch/Rbp-j signaling prevents premature endocrine and ductal cell differentiation in the pancreas. Cell Metab. 2006 Jan;3(1):59-65
1	J:129765 Goulley J, Dahl U, Baeza N, Mishina Y, Edlund H, BMP4-BMPR1A signaling in beta cells is required for and augments glucose-stimulated insulin secretion. Cell Metab. 2007 Mar;5(3):207-19
1	J:80135 Heller RS, Dichmann DS, Jensen J, Miller C, Wong G, Madsen OD, Serup P, Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation. Dev Dyn. 2002 Nov;225(3):260-70
1	J:120581 Jensen J, Heller RS, Funder-Nielsen T, Pedersen EE, Lindsell C, Weinmaster G, Madsen OD, Serup P, Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation. Diabetes. 2000 Feb;49(2):163-76
1*	J:119468 Kedees MH, Guz Y, Vuguin PM, Vargas C, Cui L, Steiner DF, Charron MJ, Teitelman G, Nestin expression in pancreatic endocrine and exocrine cells of mice lacking glucagon signaling. Dev Dyn. 2007 Mar 15;236(4):1126-1133
1	J:282308 Romer AI, Singer RA, Sui L, Egli D, Sussel L, Murine Perinatal beta-Cell Proliferation and the Differentiation of Human Stem Cell-Derived Insulin-Expressing Cells Require NEUROD1. Diabetes. 2019 Dec;68(12):2259-2271
1	J:85590 Vincent M, Guz Y, Rozenberg M, Webb G, Furuta M, Steiner D, Teitelman G, Abrogation of protein convertase 2 activity results in delayed islet cell differentiation and maturation, increased alpha-cell proliferation, and islet neogenesis. Endocrinology. 2003 Sep;144(9):4061-9
1	J:129652 Vuguin PM, Kedees MH, Cui L, Guz Y, Gelling RW, Nejathaim M, Charron MJ, Teitelman G, Ablation of the glucagon receptor gene increases fetal lethality and produces alterations in islet development and maturation. Endocrinology. 2006 Sep;147(9):3995-4006